Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana.
Identifieur interne : 000312 ( Main/Exploration ); précédent : 000311; suivant : 000313Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana.
Auteurs : Alexander J. Stockdale [Royaume-Uni] ; Richard Odame Phillips [Ghana] ; Apostolos Beloukas [Royaume-Uni] ; Lambert Tetteh Appiah [Ghana] ; David Chadwick ; Sanjay Bhagani [Royaume-Uni] ; Laura Bonnett ; Fred Stephen Sarfo [Ghana] ; Geoffrey Dusheiko [Royaume-Uni] ; Anna Maria Geretti [Royaume-Uni]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Afrique subsaharienne, Antiviraux (usage thérapeutique), Charge virale, Cirrhose du foie (diagnostic), Cirrhose du foie (épidémiologie), Co-infection (traitement médicamenteux), Femelle, Ghana, Humains, Hépatite B chronique (), Hépatite B chronique (traitement médicamenteux), Hépatite B chronique (virologie), Imagerie d'élasticité tissulaire, Infections à VIH (), Lamivudine (usage thérapeutique), Mâle, Résultat thérapeutique, Ténofovir (usage thérapeutique), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (isolement et purification), Virus de l'hépatite B (génétique), Virus de l'hépatite B (isolement et purification), Études prospectives, Études transversales.
- MESH :
- diagnostic : Cirrhose du foie.
- génétique : VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Virus de l'hépatite B.
- isolement et purification : VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Virus de l'hépatite B.
- traitement médicamenteux : Co-infection, Hépatite B chronique.
- usage thérapeutique : Antiviraux, Lamivudine, Ténofovir.
- virologie : Hépatite B chronique.
- épidémiologie : Cirrhose du foie.
- Adulte, Adulte d'âge moyen, Afrique subsaharienne, Charge virale, Femelle, Ghana, Humains, Hépatite B chronique, Imagerie d'élasticité tissulaire, Infections à VIH, Mâle, Résultat thérapeutique, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Études prospectives, Études transversales.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Adult, Africa South of the Sahara, Antiviral Agents (therapeutic use), Coinfection (drug therapy), Cross-Sectional Studies, Elasticity Imaging Techniques, Female, Ghana, HIV Infections (complications), HIV-1 (classification), HIV-1 (genetics), HIV-1 (isolation & purification), Hepatitis B virus (genetics), Hepatitis B virus (isolation & purification), Hepatitis B, Chronic (complications), Hepatitis B, Chronic (drug therapy), Hepatitis B, Chronic (virology), Humans, Lamivudine (therapeutic use), Liver Cirrhosis (diagnosis), Liver Cirrhosis (epidemiology), Male, Middle Aged, Prospective Studies, Tenofovir (therapeutic use), Treatment Outcome, Viral Load.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Lamivudine, Tenofovir.
- geographic : Africa South of the Sahara, Ghana.
- classification : HIV-1.
- complications : HIV Infections, Hepatitis B, Chronic.
- diagnosis : Liver Cirrhosis.
- drug therapy : Coinfection, Hepatitis B, Chronic.
- epidemiology : Liver Cirrhosis.
- genetics : HIV-1, Hepatitis B virus.
- isolation & purification : HIV-1, Hepatitis B virus.
- virology : Hepatitis B, Chronic.
- Adult, Cross-Sectional Studies, Elasticity Imaging Techniques, Female, Humans, Male, Middle Aged, Prospective Studies, Treatment Outcome, Viral Load.
Abstract
Antiretroviral treatment (ART) programs in sub-Saharan Africa have for many years included lamivudine as the sole hepatitis B virus (HBV) inhibitor. Long-term outcomes and the effects of introducing tenofovir as part of ART in these populations have not been characterized.
DOI: 10.1093/cid/civ421
PubMed: 26021992
Affiliations:
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Le document en format XML
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Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Bonnett, Laura" sort="Bonnett, Laura" uniqKey="Bonnett L" first="Laura" last="Bonnett">Laura Bonnett</name><affiliation><nlm:affiliation>Institute of Infection and Global Health, University of Liverpool, United Kingdom Department of Biostatistics, University of Liverpool.</nlm:affiliation><wicri:noCountry code="subField">University of Liverpool</wicri:noCountry></affiliation></author><author><name sortKey="Sarfo, Fred Stephen" sort="Sarfo, Fred Stephen" uniqKey="Sarfo F" first="Fred Stephen" last="Sarfo">Fred Stephen Sarfo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Medicine, Kwame Nkrumah University of Science and Technology Komfo Anokye Teaching Hospital, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Dusheiko, Geoffrey" sort="Dusheiko, Geoffrey" uniqKey="Dusheiko G" first="Geoffrey" last="Dusheiko">Geoffrey Dusheiko</name><affiliation wicri:level="4"><nlm:affiliation>Division of Medicine, University College London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, University College London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Geretti, Anna Maria" sort="Geretti, Anna Maria" uniqKey="Geretti A" first="Anna Maria" last="Geretti">Anna Maria Geretti</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Infection and Global Health, University of 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(isolation & purification)</term><term>Hepatitis B virus (genetics)</term><term>Hepatitis B virus (isolation & purification)</term><term>Hepatitis B, Chronic (complications)</term><term>Hepatitis B, Chronic (drug therapy)</term><term>Hepatitis B, Chronic (virology)</term><term>Humans</term><term>Lamivudine (therapeutic use)</term><term>Liver Cirrhosis (diagnosis)</term><term>Liver Cirrhosis (epidemiology)</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Tenofovir (therapeutic use)</term><term>Treatment Outcome</term><term>Viral Load</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Afrique subsaharienne</term><term>Antiviraux (usage thérapeutique)</term><term>Charge virale</term><term>Cirrhose du foie (diagnostic)</term><term>Cirrhose du foie (épidémiologie)</term><term>Co-infection (traitement médicamenteux)</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Hépatite B chronique ()</term><term>Hépatite B chronique (traitement médicamenteux)</term><term>Hépatite B chronique (virologie)</term><term>Imagerie d'élasticité tissulaire</term><term>Infections à VIH ()</term><term>Lamivudine (usage thérapeutique)</term><term>Mâle</term><term>Résultat thérapeutique</term><term>Ténofovir (usage thérapeutique)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) ()</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (isolement et purification)</term><term>Virus de l'hépatite B (génétique)</term><term>Virus de l'hépatite B (isolement et purification)</term><term>Études prospectives</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Lamivudine</term><term>Tenofovir</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Africa South of the Sahara</term><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term><term>Hepatitis B, Chronic</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Liver Cirrhosis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Cirrhose du foie</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coinfection</term><term>Hepatitis B, Chronic</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Liver Cirrhosis</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>HIV-1</term><term>Hepatitis B virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Virus de l'hépatite B</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>HIV-1</term><term>Hepatitis B virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Virus de l'hépatite B</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Co-infection</term><term>Hépatite B chronique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Lamivudine</term><term>Ténofovir</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Hépatite B chronique</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Hepatitis B, Chronic</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Cirrhose du foie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cross-Sectional Studies</term><term>Elasticity Imaging Techniques</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Treatment Outcome</term><term>Viral Load</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Afrique subsaharienne</term><term>Charge virale</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Hépatite B chronique</term><term>Imagerie d'élasticité tissulaire</term><term>Infections à VIH</term><term>Mâle</term><term>Résultat thérapeutique</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Études prospectives</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Antiretroviral treatment (ART) programs in sub-Saharan Africa have for many years included lamivudine as the sole hepatitis B virus (HBV) inhibitor. Long-term outcomes and the effects of introducing tenofovir as part of ART in these populations have not been characterized.</div></front></TEI><affiliations><list><country><li>Ghana</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement><orgName><li>University College de Londres</li></orgName></list><tree><noCountry><name sortKey="Bonnett, Laura" sort="Bonnett, Laura" uniqKey="Bonnett L" first="Laura" last="Bonnett">Laura Bonnett</name><name sortKey="Chadwick, David" sort="Chadwick, David" uniqKey="Chadwick D" first="David" last="Chadwick">David Chadwick</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Stockdale, Alexander J" sort="Stockdale, Alexander J" uniqKey="Stockdale A" first="Alexander J" last="Stockdale">Alexander J. Stockdale</name></noRegion><name sortKey="Beloukas, Apostolos" sort="Beloukas, Apostolos" uniqKey="Beloukas A" first="Apostolos" last="Beloukas">Apostolos Beloukas</name><name sortKey="Bhagani, Sanjay" sort="Bhagani, Sanjay" uniqKey="Bhagani S" first="Sanjay" last="Bhagani">Sanjay Bhagani</name><name sortKey="Dusheiko, Geoffrey" sort="Dusheiko, Geoffrey" uniqKey="Dusheiko G" first="Geoffrey" last="Dusheiko">Geoffrey Dusheiko</name><name sortKey="Geretti, Anna Maria" sort="Geretti, Anna Maria" uniqKey="Geretti A" first="Anna Maria" last="Geretti">Anna Maria Geretti</name></country><country name="Ghana"><noRegion><name sortKey="Phillips, Richard Odame" sort="Phillips, Richard Odame" uniqKey="Phillips R" first="Richard Odame" last="Phillips">Richard Odame Phillips</name></noRegion><name sortKey="Appiah, Lambert Tetteh" sort="Appiah, Lambert Tetteh" uniqKey="Appiah L" first="Lambert Tetteh" last="Appiah">Lambert Tetteh Appiah</name><name sortKey="Sarfo, Fred Stephen" sort="Sarfo, Fred Stephen" uniqKey="Sarfo F" first="Fred Stephen" last="Sarfo">Fred Stephen Sarfo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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